Updated: Mar 18, 2019
The first thing that generally comes to mind when a bro at the gym says "Deca" or Nandrolone Decanoate is "joint healing" or "alleviate joint pain" or "bulk". While Deca has a greater androgenic potential leading to more muscle mass when dosing it along side testosterone than the testosterone itself, there is little to no human studies demonstrating any miraculous joint healing properties for Nandrolone.
What if I told you that coupling Deca with test on a low dose regimen can actually lower the amount of DHT in your system and stabilize hair loss? Suddenly, nandrolone becomes a wonder drug to baldies everywhere.
"The theory underlying the possible use of nandrolone in the context of alopecia results from the fact that it does not convert to DHT but instead gets transformed into 5α-dihydro-19-nortestosterone, a molecularly distinct compound (15,25). It is thus possible that in hypogonadal males nandrolone, in addition to or in replacement for testosterone, could alleviate concerns for the development of androgenic alopecia."
The above quote from Translational Andrology and Urology journal postulates that DHT can in a sense be limited by substituting some of the TRT testosterone with nandrolone and coupling them together.
" It has also been proven that the actions of 5AR on nandrolone produce a compound that has decreased affinity and activity at the androgen receptor (15). Given that nandrolone is not converted to DHT it seems logical to assume that it would have less effect on hair loss than exogenous testosterone (with its subsequent conversion to DHT). Thus, nandrolone may be beneficial in treating hypogonadal men concerned about alopecia in the setting of TST."
Because of the 5ar-dihydro-19nors being unable to properly bind to the androgen, it has little affect on hair loss. The only downside is that due to its inhibition of DHT production, too much Nandrolone can lead to erectile dysfunction.
Study recommends a balanced ratio for maintenance of health using testosterone and nandrolone, but failed to specify the precise dosing ratio.
A good rule of thumb is 2:1 (for example: 500mg test / 250mg deca per week). However in the case of a TRT, perhaps substituting 50mg of test with Deca would achieve desired results. The implications of 5ar-dihydro-19nors blocking and inhibiting DHT conversion may be very attractive to older men seeking to retain their long flowing locks.